Spoilers ahead. Not that you care.
Full script here.
The 3 main characters are:
Tucker - fratty douchebag protagonist
Aaron - anti-social bitter friend (based on SlingBlade from the book)
Jeff - lug-headed groom to be
(note: Aaron's name has been changed to Drew for the film)
The story starts off with Tucker having sex with a deaf girl whose mid-coitus screams are interpretated by neighbours as a rape in progress. Cops are called and, hearing the screams, break in and manhandle Tucker to the ground to "rescue" deaf girl. Tucker says "Don't tase me, bro!". I'm not kidding. Deaf girl gives abuse to the cops and tells them she was about to cum.
At this early stage it's pretty obvious that it's not exactly Citizen Kane.
The next day Tucker meets up with his friends. He tells them about deaf girl and they mention he's already had a mute girl earlier in the year. Now all he needs is a blind girl as "he's 2/3 the way to a Helen Keller". We then get dialogue and scenes which explain what each of them is about. Aaron has just broken up with a long-term girlfriend after walking in on her sucking off local white rapper, "Grillionaire". He is now bitter and disillusioned with all females. Jeff is due to marry his long-term sweet heart in a few days time.
Tucker decides that the 3 of them should go to the infamous Baby Dolls strip club. It's infamous because there's a midget stripper there, although Tucker doesn't let on to the other 2 that this is why they're going.
They lie to Jeff's fiancé and off they go. They get drunk and eat McGriddles, and get drunk some more. Tucker makes fun of people who seem to exist purely to suffer an insult and then fade into the background. They go to the strip club, Aaron pisses off every stripper that comes up to them. Jeff gets drunk some more. Tucker pays a sassy stripper $200 to take Aaron home with her. Jeff gets too drunk and hits a stripper in the face by accident, he gets thrown out of the club and ends up in jail after abusing a cop. Tucker hooks up with a married woman who can't resist his charm. Tucker experiences diarrhoea in a hotel lobby. Tucker fucks a midget called Rainbow Brite. Aaron's heart of bitterness is cracked by playing GI Joe with the son of the sassy stripper. He then has sex with sassy stripper.
The fallout from Jeff's drunk tank jailtime is that Tucker is uninvited from the wedding. Inevitably he decides to show up at the reception anyways, he grabs the mic from the best man and makes a rambling speech talking about how he had sex with a midget and had diarrhoea. Amazingly everyone loves it, *slow clap*, he earns the respect of the newlyweds and the bride's Baptist family. He then unveils a bouncy castle for the kids to play on.
Everyone begins to enjoy themselves and Tucker leans back with his friends as they notice a blind woman being led by a guide dog across the room. Tucker goes after her, his friends roll their eyes like "Oh Tucker!". The End.